Because the inserts are relatively large, researchers can use cosmids to sequence overlapping fragments of a chromosome step-by-step.
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: Once inside, the DNA circularises and replicates as a plasmid rather than undergoing a lytic cycle. Advantages and Comparisons Because the inserts are relatively large, researchers can
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A cosmid is essentially a plasmid that has been "upgraded" with a specific sequence from the ) bacteriophage . Its name is a portmanteau of (cohesive end sites) and Plasmid Components: