In July 2023, Casey DeSantis narrated a campaign video for "Mamas for DeSantis," a group formed to support her husband's presidential run. The video featured a montage of imagery and her declaring, "We will not allow you to exploit their innocence to advance your agenda," targeting themes like Diversity, Equity, and Inclusion (DEI) programs and transgender rights. The video's strong rhetoric and emotional delivery became a source for GIFs, often shared with political commentary attached.
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