What (e.g., photo restoration, retro web design) do you plan to do?
Support for files up to 300,000 pixels in either dimension, essential for high-resolution printing. System Requirements for Windows
Are you looking to compare Photoshop CS with a like CS6 or Creative Cloud?
Photoshop CS introduced several tools that became staples of the professional workflow: Layer Comps:
A critical chapter in the history of Photoshop CS involves its licensing. Photoshop CS was the first version to include mandatory product activation to combat software piracy.
Adobe Photoshop CS for Windows laid the groundwork for the modern iteration of the software we use today. It paved the way for CS2, CS3, all the way up to CS6, before Adobe transitioned entirely to the subscription-based Creative Cloud (CC) model in 2013.