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: This sequence allows the DNA to be packaged into a bacteriophage protein coat. This step makes it highly efficient at infecting host cells like Escherichia coli ( E. coli ).

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Cosmids are widely used in molecular biology for cloning large DNA fragments, often up to 40-50 kilobase pairs (kbp) in size. This allows researchers to isolate and study genes that are too large to be cloned in traditional plasmid vectors. Cosmids have played a crucial role in many groundbreaking discoveries, including the Human Genome Project. : This sequence allows the DNA to be

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